SCHEMBL14960474

SCHEMBL14960474

CCOP(OCC)OCCC#N

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NLRP3 Q96P20 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16248657 0.89 NLRP3 (0.32) TSHRNLRP3
SCHEMBL1500279 0.87 ALDH1A1 (0.41) TSHRALDH1A1TDP1NLRP3TP53
SCHEMBL17943733 0.86 TSHR (0.40) TSHRALDH1A1TDP1NLRP3TP53
SCHEMBL13707340 0.79 TSHR (0.33) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL17689313 0.78 NLRP3 (0.37) TSHRALDH1A1TDP1NLRP3
SCHEMBL11132848 0.76 ALDH1A1 (0.42) ALDH1A1TP53
Water SCHEMBL27496769 0.76 ALDH1A1 (0.32) ALDH1A1TP53
SCHEMBL20295205 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5468094 0.74 ALDH1A1 (0.30) ALDH1A1
SCHEMBL22735129 0.73 ALDH1A1 (0.33) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445142-B2 Organic electrolytic solution and lithium battery employing the same SAMSUNG SDI CO., LTD. (KR) 2013-05-21 US disclosed