SCHEMBL14960686

SCHEMBL14960686

CC(OC(=O)/C=C/c1ccccc1)C(C)OC(=O)/C=C/c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 2/20 0.57
AKR1B1 P15121 2/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
TDP1 Q9NUW8 2/20 0.55
GLA P06280 1/20 0.55
LMNA P02545 4/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HCAR2 Q8TDS4 2/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23702414 0.93 AKR1B10 (0.54) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL23702413 0.93 AKR1B10 (0.54) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL15869772 0.91 AKR1B10 (0.53) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL19900155 0.91 AKR1B10 (0.53) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL5941427 0.90 AKR1B10 (0.51) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL5941424 0.90 AKR1B10 (0.51) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL133104 0.89 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL133105 0.89 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
Isopropyl Cinnamate SCHEMBL11996898 0.89 AKR1B10 (0.72) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL8854386 0.87 AKR1B10 (0.56) AKR1B10AKR1B1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952191-B2 Ester resin compositions XEROX CORPORATION (US) 2015-02-10 US disclosed
US-8952191-B2 Ester resin compositions XEROX CORPORATION (US) 2015-02-10 US disclosed
US-8936359-B2 Ink compositions incorporating ester resins XEROX CORPORATION (US) 2015-01-20 US disclosed
US-8936359-B2 Ink compositions incorporating ester resins XEROX CORPORATION (US) 2015-01-20 US disclosed
US-8906150-B2 Phase change inks containing crystalline trans-cinnamic diesters and polyterpene resins XEROX CORPORATION (US) 2014-12-09 US disclosed
US-8906150-B2 Phase change inks containing crystalline trans-cinnamic diesters and polyterpene resins XEROX CORPORATION (US) 2014-12-09 US disclosed
US-8778069-B2 Phase change inks containing oligomeric rosin esters XEROX CORPORATION (US) 2014-07-15 US disclosed
US-8778069-B2 Phase change inks containing oligomeric rosin esters XEROX CORPORATION (US) 2014-07-15 US disclosed
US-20140139591-A1 INK COMPOSITIONS INCORPORATING ESTER RESINS XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20140137767-A1 Phase Change Inks Containing Oligomeric Rosin Esters XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20140137767-A1 Phase Change Inks Containing Oligomeric Rosin Esters XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20140139591-A1 INK COMPOSITIONS INCORPORATING ESTER RESINS XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20140142335-A1 ESTER RESIN COMPOSITIONS XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20140142335-A1 ESTER RESIN COMPOSITIONS XEROX CORPORATION (US) 2014-05-22 US disclosed
US-20130131226-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Polyterpene Resins XEROX CORPORATION (US) 2013-05-23 US disclosed
US-20130131226-A1 Phase Change Inks Containing Crystalline Trans-Cinnamic Diesters and Polyterpene Resins XEROX CORPORATION (US) 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142335-A1 ESTER RESIN COMPOSITIONS ELL, ELOB, ELOC AKR1B10 1565/4885AKR1B1 2282/4885CA12 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.