Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044796 | 0.85 | ALDH1A1 (0.36) | TRPV1HSD11B1MALT1ALDH1A1LMNA | |
| SCHEMBL14960680 | 0.83 | TRIM24 (0.36) | NPSR1HRH3HSD11B1MEN1KMT2A | |
| SCHEMBL25008720 | 0.77 | HRH3 (0.31) | NPSR1P2RX7HRH3HSD11B1MEN1 | |
| SCHEMBL3418088 | 0.71 | DHODH (0.38) | TRPV1HSD11B1MALT1CYP2A6 | |
| SCHEMBL29728418 | 0.70 | ALDH1A1 (0.46) | NPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28802572 | 0.70 | ALDH1A1 (0.46) | NPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10119996 | 0.69 | KDM4E (0.47) | TRPV1HSD11B1MEN1KMT2AKDM4E | |
| SCHEMBL25082888 | 0.69 | SLC16A3 (0.32) | HSD11B1MALT1 | |
| SCHEMBL13105266 | 0.68 | CYP17A1 (0.40) | TRPV1HSD11B1KDM4EMALT1ALDH1A1 | |
| SCHEMBL12925938 | 0.67 | LMNA (0.50) | NPSR1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785646-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-22 | — | — | US | disclosed |
| US-8541613-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8501951-B2 | Process for producing amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20130131348-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130131371-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130131349-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131349-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | TRPV1 2097/4885NPSR1 731/4885P2RX7 3305/4885 |
| US-20130131371-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | TRPV1 2097/4885NPSR1 731/4885P2RX7 3305/4885 |
| US-20130131348-A1 | PROCESS FOR PRODUCING AMIDE COMPOUND | C9, F3, C5 | TRPV1 2097/4885NPSR1 731/4885P2RX7 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.