SCHEMBL14960766

SCHEMBL14960766

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5cc7c(cc5n6-c5ccc6ccccc6c5)C(C)(C)c5ccccc5-7)ccc4n(-c4ccc5ccccc5c4)c3cc21

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPK10 P53779 2/20 0.33
▸ MAPK9 P45984 1/20 0.33
▸ PIK3CD O00329 1/20 0.31
▸ PIK3CA P42336 1/20 0.31
▸ MTOR P42345 1/20 0.31
▸ LPL P06858 1/20 0.30
▸ LIPG Q9Y5X9 1/20 0.30
▸ HTR3A P46098 1/20 0.30
▸ PGR P06401 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653758 0.97 TUBB4A (0.32) MAPK10MAPK9PIK3CDPIK3CAMTOR
SCHEMBL14849756 0.95 LPL (0.34) MAPK10MAPK9PIK3CDPIK3CAMTOR
SCHEMBL10014048 0.94 PIK3CD (0.33) MAPK10MAPK9PIK3CDPIK3CAMTOR
SCHEMBL19653491 0.94 KDM4E (0.37) PIK3CDPIK3CAMTORPGR
SCHEMBL19653010 0.94 KDM4E (0.37) PIK3CDPIK3CAMTORPGR
SCHEMBL17854702 0.93 MAPK10 (0.34) MAPK10MAPK9PIK3CDPIK3CAMTOR
SCHEMBL19653038 0.93 KDM4E (0.33) PIK3CDPIK3CAMTOR
SCHEMBL17760671 0.93 KDM4E (0.33) PIK3CDPIK3CAMTOR
SCHEMBL19653759 0.92 TUBB4A (0.32) MAPK10MAPK9PIK3CDPIK3CAMTOR
SCHEMBL17446048 0.91 PIK3CD (0.31) MAPK10MAPK9PIK3CDPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9196837-B2 Compound having indenocarbazole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-11-24 — — US disclosed
US-9196837-B2 Compound having indenocarbazole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-11-24 — — US disclosed
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2013-05-23 — — US disclosed
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2013-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, SLCO1B1, SLCO2A1 MAPK10 3687/4885MAPK9 1435/4885PIK3CD 2613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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