Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 17/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.58 |
| ▸ | NQO2 | P16083 | 3/20 | 0.58 |
| ▸ | BLM | P54132 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25290441 | 0.90 | MTNR1A (0.82) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL31252456 | 0.86 | MTNR1A (0.75) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL31211536 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL25792307 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL5341347 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL5346251 | 0.85 | MTNR1A (0.73) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL14960976 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL5346043 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 | |
| SCHEMBL25028247 | 0.83 | MTNR1A (0.70) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL5349767 | 0.82 | MTNR1A (0.70) | MTNR1AMTNR1BCYP1A2NOTUMNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709483-A1 | NEW 5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE DERIVATIVES AND 6,7,8,9-TETRAHYDRO-5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE USEFUL IN THE TREATMENT OF CANCER | Institut Regional du Cancer de Montpellier (FR) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024235836-A1 | NEW 5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE DERIVATIVES AND 6,7,8,9-TETRAHYDRO-5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE USEFUL IN THE TREATMENT OF CANCER | INSTITUT REGIONAL DU CANCER DE MONTPELLIER (FR) | 2024-11-21 | — | — | WO | disclosed |
| EP-4461368-A1 | 5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE DERIVATIVES AND 6,7,8,9-TETRAHYDRO-5H-PYRROLO[3,2-B:5,4-C']DIPYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Institut Regional du Cancer de Montpellier (FR) | 2024-11-13 | — | — | EP | disclosed |
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129812-A1 | NOVEL COMPOSITIONS AND METHODS FOR TREATING CANCER | HDGF, HCCS, CCNC | MTNR1A 570/4885MTNR1B 782/4885CYP1A2 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.