SCHEMBL149632

SCHEMBL149632

[CH]=C(C)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511881 0.97 CES2 (0.46)
SCHEMBL38015 0.73 CES1 (0.52)
SCHEMBL284994 0.73 CES1 (0.47)
SCHEMBL1863798 0.73
SCHEMBL11844374 0.73 ESR1 (0.56)
SCHEMBL2462551 0.73 CES1 (0.47)
SCHEMBL1035354 0.73 ESR1 (0.56)
SCHEMBL10877617 0.73 CES2 (0.52)
SCHEMBL1800935 0.73
SCHEMBL3902058 0.73 ESR1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659034-A Preparation method of Ovatodiolide derivative and application of Ovatodiolide derivative in preparation of anticancer drugs 天津尚德药缘科技股份有限公司 2024-03-08 CN claimed
WO-2023169481-A1 TETRAHYDROISOQUINOLINE DERIVATIVE AS PAN-KRAS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 思路迪生物医药(上海)有限公司 2023-09-14 WO claimed
CN-115521621-A Wear-resistant hydrophobic liquid silicone rubber and preparation method thereof 东莞市朗晟材料科技有限公司 2022-12-27 CN claimed
CN-115368858-A Heat-conducting adhesive for circuit board and preparation method thereof 广东合正科技有限公司 2022-11-22 CN claimed
US-11254813-B2 Molded article and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-02-22 US claimed
CN-113307753-A Preparation method of thioether derivative 华侨大学 2021-08-27 CN claimed
EP-3292159-B1 HIGH SOFTENING POINT HYDROCARBON RESINS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-30 EP claimed
WO-2020140856-A1 HIGH REFRACTIVE INDEX SILICA GEL FOR FULL LAMINATION OF LIQUID CRYSTAL DISPLAY SCREEN 苏州桐力光电股份有限公司 2020-07-09 WO claimed
US-20190322856-A1 MOLDED ARTICLE AND METHOD OF PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-10-24 US claimed
CN-105969301-B A kind of organic silica gel for high-power LED encapsulation and preparation method thereof and application method 上海康达化工新材料股份有限公司 2019-10-18 CN claimed
EP-0070436-B1 STABILIZER-CONTAINING REACTIVE COMPONENTS FOR PU FOAMS, STABILIZERS AND PROCESS FOR THE PREPARATION OF THE STABILIZERS BAYER AG (DE) 1986-02-26 EP claimed
US-4565834-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1986-01-21 US claimed
EP-0047109-B1 RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP claimed
US-4430452-A POLYETHERURETHANE COPOLYMERS; CORE DISCOLORATION INHIBITION; NONSCORCHING BAYER AKTIENGESELLSCHAFT (DE) 1984-02-07 US claimed
EP-0084108-A1 Stabilized polyamides BAYER AG (DE) 1983-07-27 EP claimed
EP-0070436-A1 Stabilizer-containing reactive components for PU foams, stabilizers and process for the preparation of the stabilizers BAYER AG (DE) 1983-01-26 EP claimed
EP-0047109-A1 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-10 EP claimed
US-4098764-A STABILIZERS UNIROYAL, INC. (US) 1978-07-04 US claimed
US-3996194-A STABILIZERS UNIROYAL INC. (US) 1976-12-07 US claimed
US-3982923-A THIOCARBAMATE STAUFFER CHEMICAL COMPANY (US) 1976-09-28 US claimed