Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496320 | 0.96 | KDR (0.43) | KDRLMNAKMT2AACLYHTT | |
| SCHEMBL1496367 | 0.88 | KDR (0.53) | KDRLMNAKMT2AACLYNR4A1 | |
| SCHEMBL1496313 | 0.84 | KDM4E (0.45) | KDRLMNAKMT2AACLYHTT | |
| SCHEMBL1496312 | 0.84 | KMT2A (0.47) | KDRLMNAKMT2AACLYHTT | |
| SCHEMBL1496273 | 0.83 | KDR (0.48) | KDRLMNAKMT2AKDM4ENR4A1 | |
| SCHEMBL1496280 | 0.81 | KDR (0.53) | KDRLMNAKMT2AACLYHTT | |
| SCHEMBL1496291 | 0.81 | KDM4E (0.47) | KDRLMNAKMT2AACLYHTT | |
| SCHEMBL1496305 | 0.80 | KDR (0.50) | KDRLMNAKMT2AACLYNR4A1 | |
| SCHEMBL1496366 | 0.80 | KDR (0.66) | KDRKMT2AACLYKDM4EOPRL1 | |
| SCHEMBL1496364 | 0.79 | HTR2C (0.53) | KDRLMNAKMT2AHTTNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897774-B2 | Cyclic compound having quinolylalkylthio group | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2011-03-01 | — | — | US | claimed |