SCHEMBL1496367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496280	0.92	KDR (0.53)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496366	0.91	KDR (0.66)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496305	0.89	KDR (0.50)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496364	0.88	HTR2C (0.53)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496360	0.88	KDR (0.57)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496413	0.88	KDR (0.42)	KDRKMT2AALDH1A1GAAFLT1
	SCHEMBL1496273	0.86	KDR (0.48)	KDRKMT2AALDH1A1GAANR4A1
	SCHEMBL1496334	0.86	KDR (0.56)	KDRKMT2ALMNAMEN1L3MBTL1
	SCHEMBL1496313	0.86	KDM4E (0.45)	KDRKMT2AALDH1A1GAANR4A1
	SCHEMBL1347000	0.85	ALDH1A1 (0.47)	KDRKMT2AALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.