SCHEMBL1496366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496280	0.91	KDR (0.53)	KDRFLT1ACLYKMT2AMEN1
	SCHEMBL1347578	0.91	KDR (0.55)	KDRFLT1KMT2AMEN1OPRL1
	SCHEMBL1496367	0.91	KDR (0.53)	KDRFLT1ACLYKMT2AMEN1
	SCHEMBL1496284	0.89	KDR (0.52)	KDRFLT1NPC1ACLYKMT2A
	SCHEMBL1496305	0.88	KDR (0.50)	KDRFLT1NPC1ACLYKMT2A
	SCHEMBL1496282	0.87	KDR (0.64)	KDRFLT1NPC1TSHRACLY
	SCHEMBL1496364	0.87	HTR2C (0.53)	KDRFLT1KMT2AALDH1A1GAA
	SCHEMBL1496360	0.87	KDR (0.57)	KDRFLT1KMT2AMEN1PABPC1
	SCHEMBL1496381	0.87	NSD2 (0.56)	KDRKMT2AMEN1ALDH1A1GAA
	SCHEMBL1496334	0.85	KDR (0.56)	KDRNPC1KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.