Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964156 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL14964160 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL18974105 | 0.84 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL14904896 | 0.81 | TSHR (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14904952 | 0.81 | TSHR (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14904974 | 0.81 | TSHR (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14964159 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14968615 | 0.79 | TSHR (0.46) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14904879 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL16004219 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388112-B2 | Bisphenol derivatives and their use as androgen receptor activity modulators | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-20130131167-A1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131167-A1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | CYP19A1, AR, SHBG | ALDH1A1 666/4885TSHR 642/4885TDP1 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.