Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14443052 | 1.00 | ALDH1A1 (0.49) | ALDH1A1IKBKBIDO1MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL5630949 | 0.95 | ALDH1A1 (0.50) | ALDH1A1IKBKBMAPTKMT2AKDR | |
| Trifluoroacetic Acid SCHEMBL5630927 | 0.95 | ALDH1A1 (0.50) | ALDH1A1IKBKBMAPTKMT2AKDR | |
| SCHEMBL5630936 | 0.85 | MAPT (0.49) | ALDH1A1IKBKBMAPTKMT2AKDR | |
| SCHEMBL5630818 | 0.85 | ALDH1A1 (0.43) | ALDH1A1IKBKBMAPTKMT2AKDR | |
| SCHEMBL5630828 | 0.85 | ALDH1A1 (0.43) | ALDH1A1IKBKBMAPTKMT2AKDR | |
| SCHEMBL146908 | 0.85 | IKBKE (0.52) | ALDH1A1IKBKBIDO1MAPTKMT2A | |
| SCHEMBL146907 | 0.85 | IKBKE (0.52) | ALDH1A1IKBKBIDO1MAPTKMT2A | |
| SCHEMBL4980747 | 0.84 | ALDH1A1 (0.46) | ALDH1A1IKBKBIDO1MAPTKMT2A | |
| SCHEMBL4980755 | 0.84 | ALDH1A1 (0.46) | ALDH1A1IKBKBIDO1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |