Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 17/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 17/20 | 0.54 |
| ▸ | CDK2 | P24941 | 17/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 13/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 13/20 | 0.54 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964188 | 1.00 | CCNE2 (0.54) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14964177 | 1.00 | CCNE2 (0.54) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL14964329 | 0.99 | CCNE2 (0.54) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL14964170 | 0.99 | CCNE2 (0.54) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL14964171 | 0.99 | CCNE2 (0.54) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14977882 | 0.84 | DYRK1A (0.58) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14977880 | 0.81 | CCNE2 (0.60) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14964187 | 0.80 | CDK1 (0.59) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14964304 | 0.76 | DYRK1A (0.82) | CCNE2CCNE1CDK2CCNA2CCNA1 | |
| SCHEMBL14964249 | 0.76 | DYRK1A (0.82) | CCNE2CCNE1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450432-B2 | Polyurethane elastomer composition for electrophotographic printing and electrophotographic printing member using the same | DIC CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |