Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.56 |
| ▸ | CCNK | O75909 | 7/20 | 0.56 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.50 |
| ▸ | CDK1 | P06493 | 9/20 | 0.50 |
| ▸ | CDK9 | P50750 | 8/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.50 |
| ▸ | CDK7 | P50613 | 6/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.50 |
| ▸ | CCNH | P51946 | 4/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964303 | 1.00 | CDK2 (0.56) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL17628572 | 0.83 | CDK2 (0.66) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL14964249 | 0.80 | DYRK1A (0.82) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL14964304 | 0.80 | DYRK1A (0.82) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL14964239 | 0.78 | DYRK1A (0.54) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL19112178 | 0.76 | NPSR1 (0.67) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL30356263 | 0.76 | NPSR1 (0.67) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL19112192 | 0.76 | NPSR1 (0.67) | CDK2CCNA2CCNE1CCNKCDK12 | |
| SCHEMBL15387124 | 0.76 | NPSR1 (0.67) | CDK2CCNA2CCNE1CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL23927315 | 0.76 | NPSR1 (0.66) | CDK2CCNA2CCNE1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450342-B2 | Perharidines as CDK inhibitors | CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-05-28 | — | — | US | disclosed |