Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964264 | 1.00 | MAPK1 (0.30) | MAPK1MAPTHTT | |
| SCHEMBL14964231 | 0.92 | USP2 (0.34) | — | |
| SCHEMBL14964229 | 0.92 | USP2 (0.34) | — | |
| SCHEMBL16435032 | 0.92 | IDO1 (0.33) | — | |
| SCHEMBL16435031 | 0.92 | IDO1 (0.33) | — | |
| SCHEMBL14964216 | 0.88 | MAPT (0.37) | MAPTHTT | |
| SCHEMBL14964217 | 0.88 | MAPT (0.37) | MAPTHTT | |
| SCHEMBL4972930 | 0.86 | IDO1 (0.31) | — | |
| SCHEMBL14980203 | 0.86 | SMN1; SMN2 (0.35) | MAPK1MAPT | |
| SCHEMBL14964323 | 0.86 | IDO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |