Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964339 | 0.88 | MAPK1 (0.32) | IDO1 | |
| SCHEMBL14964343 | 0.87 | IDO1 (0.35) | IDO1 | |
| SCHEMBL16581795 | 0.82 | IDO1 (0.34) | IDO1IDO2 | |
| SCHEMBL14462388 | 0.81 | IDO1 (0.37) | IDO1 | |
| SCHEMBL14964191 | 0.80 | IDO1 (0.40) | IDO1 | |
| SCHEMBL14964265 | 0.80 | STAT5B (0.33) | — | |
| SCHEMBL14964172 | 0.79 | IDO1 (0.33) | IDO1IDO2 | |
| SCHEMBL16581924 | 0.79 | MAPK1 (0.33) | IDO1 | |
| SCHEMBL5631331 | 0.77 | IDO1 (0.41) | IDO1 | |
| SCHEMBL5631323 | 0.77 | IDO1 (0.41) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |