SCHEMBL14964832

SCHEMBL14964832

CN(C)C(=O)NC[C@@]1(C)C[C@H](NC(=O)N(C)C)CC(C)(C)C1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
TDP1 Q9NUW8 1/20 0.35
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30
PBK Q96KB5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3837629 1.00 TSHR (0.59) TSHRTDP1OPRM1OPRL1PBK
SCHEMBL12745259 0.85 TSHR (0.56) TSHRTDP1OPRM1OPRL1
SCHEMBL18373659 0.83 TSHR (0.57) TSHRTDP1
SCHEMBL17346759 0.83 TSHR (0.57) TSHRTDP1
SCHEMBL13098673 0.82 TSHR (0.44) TSHROPRM1OPRL1
SCHEMBL25477747 0.80 TSHR (0.51) TSHRTDP1
SCHEMBL17552110 0.80 TSHR (0.57) TSHRTDP1
SCHEMBL22198290 0.80 TSHR (0.44) TSHR
SCHEMBL17346766 0.79 TSHR (0.50) TSHRTDP1
SCHEMBL17552042 0.79 TSHR (0.52) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663609-B2 Use of N,N′-(dimethyl) urones and method for curing epoxy resin compositions ALZCHEM AG (DE) 2017-05-30 US disclosed
EP-2780388-B1 USE OF N,N'-(DIMETHYL) URONS AND METHOD FOR CURING EPOXY RESIN COMPOSITIONS ALZCHEM AG (DE) 2015-05-06 EP disclosed
US-20140357762-A1 USE OF N,N'-(DIMETHYL) URONES AND METHOD FOR CURING EPOXY RESIN COMPOSITIONS ALZCHEM AG (DE) 2014-12-04 US disclosed
EP-2780388-A1 USE OF N,N'-(DIMETHYL) URONS AND METHOD FOR CURING EPOXY RESIN COMPOSITIONS AlzChem AG (DE) 2014-09-24 EP disclosed
WO-2013072356-A1 USE OF N,N'-(DIMETHYL) URONS AND METHOD FOR CURING EPOXY RESIN COMPOSITIONS ALZCHEM AG (DE) 2013-05-23 WO disclosed