Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811115 | 0.82 | TSHR (0.48) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL18786168 | 0.82 | TSHR (0.48) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL3837629 | 0.82 | TSHR (0.59) | TSHROPRM1OPRL1 | |
| SCHEMBL14964832 | 0.82 | TSHR (0.59) | TSHROPRM1OPRL1 | |
| SCHEMBL30130345 | 0.80 | TSHR (0.41) | TSHR | |
| SCHEMBL17171621 | 0.79 | HSD17B10 (0.46) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL13647776 | 0.79 | TSHR (0.68) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL17172386 | 0.78 | TSHR (0.44) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL12390923 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1 | |
| SCHEMBL24675347 | 0.77 | OPRM1 (0.45) | TSHROPRM1OPRL1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273008-A1 | POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS | SIKA TECHNOLOGY AG (CH) | 2010-10-28 | — | — | US | disclosed |
| US-20100273008-A1 | POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS | SIKA TECHNOLOGY AG (CH) | 2010-10-28 | — | — | US | disclosed |
| WO-2009065913-A1 | POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS | SIKA TECHNOLOGY AG (CH) | 2009-05-28 | — | — | WO | disclosed |
| EP-2062926-A1 | Polyurethane polymer for reversible adhesive joints | Sika Technology AG (CH) | 2009-05-27 | — | — | EP | disclosed |