Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964894 | 1.00 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14964917 | 0.87 | ALDH1A1 (0.80) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14964918 | 0.87 | ALDH1A1 (0.80) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14965065 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14964780 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14965063 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14964781 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14968775 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14968774 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14965018 | 0.84 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |