Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.80 |
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | RAB9A | P51151 | 7/20 | 0.80 |
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964917 | 1.00 | ALDH1A1 (0.80) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14964780 | 0.99 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14965063 | 0.99 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14965065 | 0.99 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14964781 | 0.99 | ALDH1A1 (0.78) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14968775 | 0.89 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14968774 | 0.89 | ALDH1A1 (1.00) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14964895 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14965017 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14965018 | 0.87 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |