Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965286 | 0.90 | CDK8 (0.37) | CDK8 | |
| SCHEMBL16293967 | 0.86 | — | — | |
| SCHEMBL14965154 | 0.82 | — | — | |
| SCHEMBL14964982 | 0.80 | HRH3 (0.40) | HRH3 | |
| SCHEMBL14965144 | 0.79 | HRH3 (0.37) | HRH3 | |
| SCHEMBL14968786 | 0.76 | HRH3 (0.35) | HRH3 | |
| SCHEMBL14964756 | 0.76 | HRH3 (0.34) | HRH3 | |
| SCHEMBL14969446 | 0.76 | MEN1 (0.45) | — | |
| SCHEMBL28087471 | 0.74 | LTA4H (0.40) | HRH3 | |
| SCHEMBL16293417 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |