Spermine

Spermine

SCHEMBL14965

NCCCNCCCCNCCCN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 1.00
CA6 P23280 5/20 1.00
CA7 P43166 5/20 1.00
CA9 Q16790 5/20 1.00
CA14 Q9ULX7 5/20 1.00
CA5B Q9Y2D0 5/20 1.00
CA2 P00918 4/20 1.00
CA4 P22748 4/20 1.00
CA5A P35218 4/20 1.00
ALOX15 P16050 3/20 1.00
F13A1 P00488 2/20 1.00
CYP1A2 P05177 2/20 1.00
THPO P40225 2/20 1.00
CASP2 P42575 2/20 1.00
MEN1 O00255 2/20 1.00
RECQL P46063 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP2C19 P33261 1/20 1.00
HSD17B10 Q99714 1/20 1.00
CA3 P07451 3/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spermine SCHEMBL288720 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL30446193 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL8514287 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL12002491 0.96 CA12 (0.93) CA12CA6CA7CA9CA14
Spermine SCHEMBL431884 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL1167355 0.96 UBE2N (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL6328887 0.96 CA12 (0.93) CA12CA6CA7CA9CA14
Spermine SCHEMBL1273895 0.96 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL3159000 0.96 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL995526 0.96 CA12 (0.93) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 53526 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146278-A1 Biological Substance Treatment Method, Reaction Detection Method, Biological Substance Treatment Apparatus, and Reaction Detection Apparatus JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2026-05-28 US claimed
EP-4261265-B1 PLUGGING AGENT FOR OIL EXTRACTION IN OILFIELD AND A PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-27 EP claimed
EP-4746924-A1 NON-NATURAL BUILDING BLOCKS FOR ENHANCED TRANSLATION AND STABILITY OF MRNA Eleven Therapeutics Ltd (IL) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122080927-A Biogenic amine visual detection method based on carbon dot/quantum dot ratio fluorescent probe and application 2026-05-26 CN claimed
CN-120966818-B Super-long fragment DNA extraction kit and application 武汉贝纳科技有限公司 2026-05-22 CN claimed
WO-2026106607-A1 CHEMICAL STRUCTURES THAT CONTROL METABOLIC ELIMINATION OF AMINOSTEROLS BAZ Therapeutics, Inc. (US) 2026-05-21 WO claimed
WO-2026107397-A1 CHARACTERIZATION OF THE EPIGENETIC LANDSCAPE IN COMPLEX FLUIDS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2026-05-21 WO claimed
US-12629343-B2 Multi-layer transdermal drug delivery system containing ibuprofen or structural analogue thereof Demotech, Inc. (CN) 2026-05-19 US claimed
US-12629336-B2 Compositions and methods of use thereof for treatment of mastitis CUREMAST, INC. (US) 2026-05-19 US claimed
US-4495274-A LOW SPEED MATERIAL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-01-22 US claimed
US-4419444-A AGGLUTINATION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM (FR) 1983-12-06 US claimed
EP-0093002-A2 A direct-positive silver halide photographic material KONICA CORPORATION (JP) 1983-11-02 EP claimed
US-4316882-A SKIN TESTING USING N-PENCILLOYL AMINES LEVINE BERNARD B 1982-02-23 US claimed
US-4228147-A A PENICYLOYLAMINE, BENZYLPENICILLIN, SODIUM BENZYLPENICILLOATE, AND A SOLVENT LEVINE BERNARD B 1980-10-14 US claimed
US-4224416-A Degradable plastic composition containing amine OWENS-ILLINOIS, INC. (US) 1980-09-23 US claimed
US-4217338-A MEDICAL DIAGNOSIS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 1980-08-12 US claimed
US-4101720-A Degradable plastic OWENS-ILLINOIS, INC. (US) 1978-07-18 US claimed
US-4004996-A Fluorination of organic compounds MERCK & CO., INC. (US) 1977-01-25 US claimed
US-3977942-A ARGININE, ORNITHINE, LYSINE, POLYAMINES MERCK & CO., INC. (US) 1976-08-31 US claimed