Spermidine

Spermidine

SCHEMBL15618

NCCCCNCCCN

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 1.00
CA6 P23280 5/20 1.00
CA7 P43166 5/20 1.00
CA9 Q16790 5/20 1.00
CA14 Q9ULX7 5/20 1.00
CA5B Q9Y2D0 5/20 1.00
CA2 P00918 4/20 1.00
CA4 P22748 4/20 1.00
CA5A P35218 4/20 1.00
ALOX15 P16050 3/20 1.00
CA3 P07451 3/20 1.00
F13A1 P00488 2/20 1.00
CYP1A2 P05177 2/20 1.00
THPO P40225 2/20 1.00
CA1 P00915 2/20 1.00
CYP2C9 P11712 1/20 1.00
PKM P14618 1/20 1.00
TSHR P16473 1/20 1.00
MTOR P42345 1/20 1.00
LMNA P02545 3/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3165201 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermidine SCHEMBL8073115 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermidine SCHEMBL288987 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL3175232 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL431884 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL288605 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL5802297 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
Spermidine SCHEMBL6253721 1.00 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL4861043 0.97 CA12 (0.93) CA12CA6CA7CA9CA14
Spermidine SCHEMBL573651 0.97 LMNA (1.00) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 69887 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 US claimed
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
EP-4261265-B1 PLUGGING AGENT FOR OIL EXTRACTION IN OILFIELD AND A PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-27 EP claimed
EP-3727419-B1 A COMBINATION OF SPERMIDINE AND HIGH PROTEIN COMPOSITION FOR INDUCTION OF AUTOPHAGY NESTLE SA (CH) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122075771-A Hydrogel dressing for diabetic foot wound surface and preparation thereof 2026-05-26 CN claimed
CN-122081151-A Lactobacillus buchneri LW2 capable of reducing nitrite content and application thereof 2026-05-26 CN claimed
CN-122074090-A Diversified phage synthesis and engineering platform 修兰教育基金管理公司 2026-05-22 CN claimed
CN-120966818-B Super-long fragment DNA extraction kit and application 武汉贝纳科技有限公司 2026-05-22 CN claimed
US-4495274-A LOW SPEED MATERIAL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-01-22 US claimed
EP-0116693-A1 An immunopotentiator having spermidine or its pharmacologically acceptable salt as active ingredient MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1984-08-29 EP claimed
EP-0096654-A2 Process for sizing paper with anionic, hydrophobic sizing agents and cationic retention agents CIBA-GEIGY AG (CH) 1983-12-21 EP claimed
US-4419444-A AGGLUTINATION INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE-INSERM (FR) 1983-12-06 US claimed
EP-0093002-A2 A direct-positive silver halide photographic material KONICA CORPORATION (JP) 1983-11-02 EP claimed
US-4355116-A ION EXCHANGE RESINS ALLIED CORPORATION (US) 1982-10-19 US claimed
US-4316882-A SKIN TESTING USING N-PENCILLOYL AMINES LEVINE BERNARD B 1982-02-23 US claimed
US-4228147-A A PENICYLOYLAMINE, BENZYLPENICILLIN, SODIUM BENZYLPENICILLOATE, AND A SOLVENT LEVINE BERNARD B 1980-10-14 US claimed
US-4217338-A MEDICAL DIAGNOSIS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 1980-08-12 US claimed
US-3977942-A ARGININE, ORNITHINE, LYSINE, POLYAMINES MERCK & CO., INC. (US) 1976-08-31 US claimed