Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966146 | 0.91 | CHRM1 (0.36) | CHRM1ALDH1A1KCNH2LMNA | |
| SCHEMBL14966080 | 0.86 | ALDH1A1 (0.39) | KDM4EALDH1A1KCNH2LMNAMAPT | |
| SCHEMBL14965946 | 0.84 | CYP1A2 (0.46) | SIGMAR1 | |
| SCHEMBL14965376 | 0.84 | CHRM1 (0.35) | CHRM1SIGMAR1ALDH1A1KCNH2MAPT | |
| SCHEMBL14965891 | 0.82 | CHRM1 (0.36) | CHRM1ALDH1A1KCNH2MAPT | |
| SCHEMBL14965843 | 0.81 | CHRM1 (0.48) | CHRM1SMN1; SMN2KCNH2LMNA | |
| SCHEMBL14965582 | 0.80 | HSD17B10 (0.38) | CHRM1ALDH1A1KCNH2LMNAMAPT | |
| SCHEMBL14965586 | 0.79 | EPHX2 (0.51) | THRBCHRM1KCNH2MAPT | |
| SCHEMBL14965275 | 0.79 | ALDH1A1 (0.37) | CHRM1ALDH1A1KCNH2LMNAMAPT | |
| SCHEMBL14966212 | 0.79 | HSD11B1 (0.44) | CHRM1KDM4EALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |