Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070660 | 0.83 | HTT (0.58) | TDP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3440911 | 0.82 | PRKCI (0.61) | ALDH1A1HSD17B10MAPTNPC1RAB9A | |
| SCHEMBL11027199 | 0.81 | HDAC1 (0.60) | TDP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL1496520 | 0.80 | MEN1 (0.54) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL1496463 | 0.78 | HTT (0.67) | TDP1ALDH1A1PKMMAPK1MAPT | |
| SCHEMBL8352164 | 0.77 | HSD17B10 (0.55) | TDP1ALDH1A1HSD17B10PKMMAPK1 | |
| SCHEMBL5881733 | 0.77 | PTGER4 (0.56) | TDP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL10763967 | 0.75 | RAB9A (0.58) | ALDH1A1HSD17B10MAPTMEN1RAB9A | |
| SCHEMBL7811924 | 0.75 | HTT (0.56) | TDP1ALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL7970378 | 0.75 | TDP1 (0.46) | TDP1HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |