Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496476 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL1496563 | 0.80 | TDP1 (0.50) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL11317896 | 0.78 | EPHX2 (0.58) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL11320899 | 0.75 | KMT2A (0.68) | MEN1KMT2AHDAC3HDAC1ALDH1A1 | |
| SCHEMBL11317939 | 0.75 | POLB (0.60) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL11314927 | 0.74 | KMT2A (0.70) | MEN1KMT2AHDAC1ALDH1A1L3MBTL1 | |
| SCHEMBL9525046 | 0.73 | EPHX2 (0.60) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL11318494 | 0.72 | TDP1 (0.65) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL11315783 | 0.72 | KMT2A (0.72) | MEN1KMT2AHDAC3HDAC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9626414 | 0.72 | EPHX2 (0.58) | MEN1KMT2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |