Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IL18 | Q14116 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980418 | 0.89 | CA12 (0.44) | SCN9AKDM4EMAPTCYP19A1GRIN1 | |
| SCHEMBL28239877 | 0.89 | CA12 (0.44) | SCN9AKDM4EMAPTCYP19A1GRIN1 | |
| SCHEMBL13174142 | 0.89 | CA12 (0.44) | SCN9AKDM4EMAPTCYP19A1GRIN1 | |
| SCHEMBL11581783 | 0.85 | CYP3A4 (0.44) | SCN9AMEN1KMT2A | |
| SCHEMBL15981026 | 0.79 | PARP15 (0.50) | SCN9APARP15PARP10PARP2KDM4E | |
| SCHEMBL7041250 | 0.77 | PARP15 (0.63) | SCN9APARP15PARP10PARP2KDM4E | |
| SCHEMBL8852392 | 0.77 | PARP15 (0.63) | SCN9APARP15PARP10PARP2KDM4E | |
| SCHEMBL3233441 | 0.74 | LTA4H (0.59) | SCN9APARP15PARP10PARP2KDM4E | |
| SCHEMBL5827966 | 0.74 | PARP15 (0.49) | PARP15PARP10PARP2KDM4EMEN1 | |
| SCHEMBL13891122 | 0.74 | CA12 (0.41) | KDM4EMAPTCYP19A1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072758-A1 | PYRIMIDINE DIOL AMIDES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2013-05-23 | — | — | WO | disclosed |