Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | GLS | O94925 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965929 | 0.91 | USP2 (0.39) | USP2HTTGFERROCK2ROCK1 | |
| SCHEMBL14965548 | 0.90 | CHRM1 (0.52) | CHRM1KCNH2USP2HTT | |
| SCHEMBL14965622 | 0.88 | CHRM1 (0.50) | CHRM1KCNH2USP2HTT | |
| SCHEMBL14966262 | 0.88 | POLB (0.49) | USP2HTTPOLB | |
| SCHEMBL14965557 | 0.87 | DRD4 (0.48) | CHRM1KCNH2EPHX2 | |
| SCHEMBL14965591 | 0.87 | CHRM3 (0.47) | CHRM1KCNH2ROCK2ROCK1MAPK14 | |
| SCHEMBL14965784 | 0.86 | CHRM1 (0.49) | CHRM1KCNH2HTTROCK2ROCK1 | |
| SCHEMBL14966200 | 0.86 | CHRM1 (0.44) | CHRM1KCNH2EPHX2 | |
| SCHEMBL14966219 | 0.83 | CA1 (0.48) | CHRM1KCNH2USP2HTTPOLB | |
| SCHEMBL14965804 | 0.82 | KMT2A (0.41) | CHRM1KCNH2USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |