Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965548 | 0.98 | CHRM1 (0.52) | CHRM1KCNH2GAAKMT2APTGS1 | |
| SCHEMBL14965849 | 0.88 | CHRM1 (0.44) | CHRM1KCNH2USP2HTT | |
| SCHEMBL14965373 | 0.87 | CA1 (0.48) | KMT2AMEN1USP2HTT | |
| SCHEMBL14966219 | 0.87 | CA1 (0.48) | CHRM1KCNH2KMT2AUSP2HTT | |
| SCHEMBL14965804 | 0.86 | KMT2A (0.41) | CHRM1KCNH2KMT2AMEN1USP2 | |
| SCHEMBL14965624 | 0.86 | CHRM1 (0.57) | CHRM1KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL14965737 | 0.85 | CHRM1 (0.49) | CHRM1KCNH2 | |
| SCHEMBL14966217 | 0.85 | CHRM1 (0.50) | CHRM1KCNH2GAAKMT2APTGS1 | |
| SCHEMBL14965565 | 0.84 | KMT2A (0.43) | KMT2AMEN1USP2HTT | |
| SCHEMBL14965365 | 0.84 | CHRM1 (0.49) | CHRM1KCNH2KMT2APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |