Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965955 | 0.90 | MAPK1 (0.44) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL14965726 | 0.90 | NPC1 (0.45) | SMN1; SMN2KMT2AMAPTGAAPOLB | |
| SCHEMBL14965906 | 0.87 | PANK3 (0.42) | SMN1; SMN2MAPTGAAFAAHLMNA | |
| SCHEMBL14965945 | 0.87 | BLM (0.55) | SMN1; SMN2KMT2ACA12CA1CA2 | |
| SCHEMBL14966229 | 0.85 | KDM4E (0.41) | SMN1; SMN2KMT2ACA1CA2GAA | |
| SCHEMBL14965794 | 0.79 | NPC1 (0.59) | SMN1; SMN2KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL14965755 | 0.77 | EPHX2 (0.50) | POLB | |
| SCHEMBL14966075 | 0.77 | KDM4E (0.46) | SMN1; SMN2KMT2AALDH1A1LMNAHTT | |
| SCHEMBL14965880 | 0.76 | P2RY12 (0.38) | KMT2APOLBALDH1A1LMNA | |
| SCHEMBL14965586 | 0.76 | EPHX2 (0.51) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |