Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965955 | 0.87 | MAPK1 (0.44) | GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14966280 | 0.87 | SMN1; SMN2 (0.52) | PANK3FAAHGAALMNAMAPT | |
| SCHEMBL14965726 | 0.87 | NPC1 (0.45) | FAAHGAALMNAMAPTHTT | |
| SCHEMBL14965945 | 0.85 | BLM (0.55) | FAAHLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL14966084 | 0.79 | SLC6A9 (0.41) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL14965998 | 0.78 | CYP11B2 (0.45) | FAAH | |
| SCHEMBL14966123 | 0.77 | KMT2A (0.52) | NAMPTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL14966236 | 0.76 | PKM (0.49) | GAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL14966075 | 0.74 | KDM4E (0.46) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL14965986 | 0.74 | KCNJ1 (0.41) | FAAHLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |