Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | PMM2 | O15305 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966321 | 0.86 | SMN1; SMN2 (0.46) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14966484 | 0.85 | KEAP1 (0.46) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14965912 | 0.81 | SMN1; SMN2 (0.51) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14966265 | 0.81 | KMT2A (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14966104 | 0.80 | SMN1; SMN2 (0.47) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29480967 | 0.79 | NPC1 (0.67) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22552282 | 0.79 | NPC1 (0.67) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14965987 | 0.79 | NPC1 (0.59) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14966623 | 0.79 | NPC1 (0.44) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14965892 | 0.76 | NPC1 (0.46) | RAB9ANPC1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |