SCHEMBL14966580

SCHEMBL14966580

COc1ccc(C2(C(=O)OC3CCCC3)OC2(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.39
EPHX2 P34913 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
EPHX1 P07099 1/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16110315 0.99 MEN1 (0.43) MEN1KMT2AHTTEPHX2L3MBTL1
SCHEMBL16109041 0.97 MEN1 (0.39) MEN1KMT2AHTTEPHX2L3MBTL1
SCHEMBL16109692 0.95 MEN1 (0.43) MEN1KMT2AHTTEPHX2L3MBTL1
SCHEMBL14967891 0.86 ADORA2B (0.39) MEN1KMT2AL3MBTL1MAPK1
SCHEMBL14966886 0.85 TDP1 (0.40) MEN1KMT2AL3MBTL1MAPK1
SCHEMBL14968283 0.85 SLC6A4 (0.40) MEN1KMT2AHTTEPHX2L3MBTL1
SCHEMBL14967068 0.85 MEN1 (0.40) MEN1KMT2AHTTEPHX2L3MBTL1
SCHEMBL14967950 0.84 ADORA2B (0.39) L3MBTL1MAPK1SLC6A4SLC6A3
SCHEMBL14968189 0.84 EPHX2 (0.41) MEN1KMT2AEPHX2L3MBTL1ATM
SCHEMBL14968280 0.84 EPHX2 (0.41) MEN1KMT2AEPHX2L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed