SCHEMBL14966817

SCHEMBL14966817

CCCOC(=O)C12CCCCC1(c1ccc(C)cc1)O2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ MAPT P10636 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ TSHR P16473 2/20 0.39
▸ MEN1 O00255 3/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ PRCP P42785 1/20 0.36
▸ SIGMAR1 Q99720 1/20 0.36
▸ POLB P06746 1/20 0.35
▸ CHRM2 P08172 2/20 0.34
▸ CHRM1 P11229 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ APOBEC3A P31941 1/20 0.34
▸ APOBEC3G Q9HC16 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967893 0.99 OPRM1 (0.39) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967894 0.97 OPRM1 (0.40) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967382 0.93 MEN1 (0.42) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967657 0.91 MEN1 (0.39) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967941 0.91 MEN1 (0.41) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967606 0.91 OPRM1 (0.48) OPRM1ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL14968009 0.90 MEN1 (0.38) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14967417 0.90 MEN1 (0.38) OPRM1ALDH1A1MAPTTSHRMEN1
SCHEMBL14967978 0.90 MEN1 (0.40) OPRM1ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL14968249 0.90 OPRM1 (0.47) OPRM1ALDH1A1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 — — US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 — — US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 — — US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 — — US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 — — US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 — — EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 — — US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 — — EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 — — WO disclosed
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