SCHEMBL14967978

SCHEMBL14967978

CCCCOC(=O)C12CCCC1(c1ccc(C)cc1)O2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ OPRM1 P35372 1/20 0.38
▸ CNR2 P34972 2/20 0.36
▸ CNR1 P21554 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ TSHR P16473 3/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ ESR1 P03372 3/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ NR1H2 P55055 1/20 0.33
▸ RNASEL Q05823 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967382 0.98 MEN1 (0.42) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14967941 0.96 MEN1 (0.41) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14968054 0.96 OPRM1 (0.38) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14968035 0.95 TSHR (0.37) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14967657 0.94 MEN1 (0.39) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14968009 0.93 MEN1 (0.38) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14967417 0.93 MEN1 (0.38) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14967894 0.93 OPRM1 (0.40) MEN1KMT2AOPRM1ALDH1A1TSHR
SCHEMBL14967116 0.92 MEN1 (0.38) MEN1KMT2AOPRM1CNR2CNR1
SCHEMBL14966817 0.90 OPRM1 (0.40) MEN1KMT2AOPRM1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 — — US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 — — US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 — — US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 — — US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 — — US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 — — EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 — — US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 — — EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 — — WO disclosed
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