SCHEMBL14967202

SCHEMBL14967202

CCCCOC(=O)C1(CC)OC1c1ccc(OC)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.41
ALDH1A1 P00352 6/20 0.40
GAA P10253 3/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 3/20 0.38
TSHR P16473 3/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967640 0.97 MIF (0.39) MIFALDH1A1GAAHSD17B10HPGD
SCHEMBL14967890 0.96 MIF (0.39) MIFALDH1A1GAAHSD17B10HPGD
SCHEMBL14967171 0.94 ALDH1A1 (0.41) MIFALDH1A1GAAHSD17B10HPGD
SCHEMBL14967685 0.88 TSHR (0.37) ALDH1A1HSD17B10KDM4ELMNAKMT2A
SCHEMBL14968170 0.88 ALDH1A1 (0.49) ALDH1A1GAAHSD17B10HPGDKDM4E
SCHEMBL16110018 0.86 ALDH1A1 (0.42) MIFALDH1A1GAAHSD17B10HPGD
SCHEMBL14967680 0.85 ALDH1A1 (0.42) ALDH1A1GAAHSD17B10HPGDKDM4E
SCHEMBL14967526 0.85 TSHR (0.38) ALDH1A1HSD17B10KDM4ELMNAKMT2A
SCHEMBL14967575 0.84 HSD17B10 (0.40) ALDH1A1HSD17B10KDM4ELMNAKMT2A
SCHEMBL16110259 0.84 ALDH1A1 (0.40) MIFALDH1A1GAAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed