Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967138 | 0.86 | L3MBTL1 (0.72) | L3MBTL1TDP1CYP4A11MAPTRAB9A | |
| SCHEMBL14966824 | 0.84 | L3MBTL1 (0.52) | L3MBTL1TDP1CYP4A11MAPTRAB9A | |
| SCHEMBL14967118 | 0.84 | JAK2 (0.53) | MAPTHPGDLMNAJAK2GAA | |
| SCHEMBL17844325 | 0.83 | HPGD (0.57) | L3MBTL1CYP4A11MAPTRAB9AHPGD | |
| SCHEMBL8409671 | 0.82 | ABCB1 (0.51) | L3MBTL1TDP1MAPTRAB9AHPGD | |
| SCHEMBL5392156 | 0.81 | MAPT (0.77) | L3MBTL1TDP1CYP4A11MAPTRAB9A | |
| SCHEMBL8409674 | 0.80 | L3MBTL1 (0.48) | L3MBTL1TDP1CYP4A11MAPTRAB9A | |
| SCHEMBL14967229 | 0.79 | L3MBTL1 (0.71) | L3MBTL1TDP1CYP4A11MAPTRAB9A | |
| SCHEMBL15079848 | 0.78 | GAA (0.62) | MAPTRAB9ALMNAJAK2GAA | |
| SCHEMBL1833210 | 0.78 | GAA (0.67) | MAPTRAB9ALMNAJAK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780014-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013075083-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2013-05-23 | — | — | WO | disclosed |