Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20887673 | 0.86 | TDP1 (0.54) | HPGDLMNAL3MBTL1ALDH1A1MGLL | |
| SCHEMBL17844306 | 0.86 | NPC1 (0.59) | HPGDLMNARAB9AMAPTPDE4A | |
| SCHEMBL8418846 | 0.86 | L3MBTL1 (0.50) | LMNAL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL1782909 | 0.86 | HPGD (0.72) | HPGDLMNAL3MBTL1CA1CA2 | |
| SCHEMBL29136473 | 0.85 | LMNA (0.74) | HPGDLMNAL3MBTL1CA1CA2 | |
| SCHEMBL14967232 | 0.83 | L3MBTL1 (0.53) | HPGDLMNAL3MBTL1ALDH1A1MGLL | |
| SCHEMBL29136465 | 0.82 | LMNA (0.61) | HPGDLMNAL3MBTL1RAB9ANPC1 | |
| SCHEMBL12650499 | 0.80 | CA12 (0.56) | HPGDLMNAL3MBTL1CA1CA2 | |
| SCHEMBL8151382 | 0.80 | SCN9A (0.48) | HPGDLMNACA1CA2ALDH1A1 | |
| Isovanillic Acid Methyl Ester SCHEMBL1561379 | 0.79 | P4HB (0.47) | MAPTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233847-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex Suisse SA (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098005-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2016-06-23 | — | — | WO | disclosed |