SCHEMBL14967306

SCHEMBL14967306

O=C(OC1CC1)C1(c2ccccc2)OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 11/20 0.43
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 2/20 0.36
EPHX2 P34913 1/20 0.34
LMNA P02545 1/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
CHRM4 P08173 9/20 0.34
CHRM5 P08912 9/20 0.34
CHRM1 P11229 9/20 0.34
CHRM2 P08172 8/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967030 0.94 CHRM3 (0.44) CHRM3MEN1KMT2AHTTLMNA
SCHEMBL14967957 0.94 CHRM3 (0.44) CHRM3MEN1KMT2AHTTLMNA
SCHEMBL14967803 0.93 CHRM3 (0.46) CHRM3MEN1KMT2AF2PRSS1
SCHEMBL16108989 0.85 SCN1A (0.38) CHRM3MEN1KMT2ATDP1
SCHEMBL16109692 0.82 MEN1 (0.43) MEN1KMT2AHTTEPHX2
SCHEMBL14967884 0.81 CHRM3 (0.46) CHRM3MEN1KMT2AHTTLMNA
SCHEMBL14968070 0.81 CHRM3 (0.49) CHRM3MEN1KMT2AHTTLMNA
SCHEMBL14966942 0.80 KMT2A (0.47) MEN1KMT2AHTTLMNA
SCHEMBL14967891 0.80 ADORA2B (0.39) MEN1KMT2ATDP1
SCHEMBL14967423 0.80 CHRM3 (0.51) CHRM3MEN1KMT2AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed