SCHEMBL14967957

SCHEMBL14967957

O=C(OC1CCCC1)C1(c2ccccc2)OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 2/20 0.44
TDP1 Q9NUW8 1/20 0.40
FABP7 O15540 1/20 0.40
FABP5 Q01469 1/20 0.40
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
BCHE P06276 1/20 0.37
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967803 0.99 CHRM3 (0.46) CHRM3TDP1FABP7FABP5F2
SCHEMBL14967030 0.97 CHRM3 (0.44) CHRM3TDP1FABP7FABP5F2
SCHEMBL14967306 0.94 CHRM3 (0.43) CHRM3TDP1F2PRSS1MEN1
SCHEMBL14967891 0.86 ADORA2B (0.39) TDP1MEN1KMT2ATP53POLB
SCHEMBL14966886 0.85 TDP1 (0.40) CHRM3TDP1NPSR1MEN1KMT2A
SCHEMBL14966580 0.83 MEN1 (0.41) CYP3A4CYP2C19MEN1KMT2ANPC1
SCHEMBL14967950 0.83 ADORA2B (0.39) CHRM3TDP1TP53POLBADORA2B
SCHEMBL14967476 0.83 CHRM3 (0.48) CHRM3TDP1FABP7FABP5FAAH
SCHEMBL14967908 0.83 CHRM3 (0.45) CHRM3TDP1FABP7FABP5F2
SCHEMBL16110315 0.82 MEN1 (0.43) CYP3A4CYP2C19MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed