Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967507 | 1.00 | DGAT1 (0.60) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL14968206 | 0.90 | DGAT1 (0.53) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL15073375 | 0.90 | DGAT1 (0.48) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL15055252 | 0.87 | DGAT1 (0.49) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL15055254 | 0.87 | DGAT1 (0.49) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL15055224 | 0.83 | DGAT1 (0.51) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL14971569 | 0.83 | DGAT1 (0.51) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL14971619 | 0.80 | DGAT1 (0.77) | DGAT1KCNH2SOAT1ADORA2A | |
| SCHEMBL14971546 | 0.80 | DGAT1 (0.42) | DGAT1KCNH2SOAT1ADORA2AERN1 | |
| SCHEMBL14971566 | 0.80 | DGAT1 (0.42) | DGAT1KCNH2SOAT1ADORA2AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |