SCHEMBL14967743

SCHEMBL14967743

CCCCCOC(=O)C1OC1(CC)c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.39
ALDH1A1 P00352 3/20 0.39
PPARG P37231 3/20 0.38
LMNA P02545 2/20 0.38
NPFFR1 Q9GZQ6 1/20 0.37
NPFFR2 Q9Y5X5 1/20 0.37
TSHR P16473 3/20 0.37
TP53 P04637 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
POLB P06746 2/20 0.36
KMT2A Q03164 1/20 0.36
STS P08842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968175 0.99 PPARG (0.39) MIFALDH1A1PPARGLMNATSHR
SCHEMBL14967638 0.97 MIF (0.41) MIFALDH1A1LMNATSHRMAPK1
SCHEMBL14967899 0.91 CHRM2 (0.37) MIFALDH1A1LMNATSHRKMT2A
SCHEMBL16109650 0.88 PPARG (0.39) ALDH1A1PPARGLMNATSHRTP53
SCHEMBL16109766 0.86 PPARG (0.41) ALDH1A1PPARGLMNATSHRTP53
SCHEMBL16108654 0.86 TSHR (0.37) ALDH1A1PPARGLMNATSHRCYP3A4
SCHEMBL14967067 0.86 PPARG (0.48) ALDH1A1PPARGLMNATSHRTP53
SCHEMBL14967027 0.86 ALDH1A1 (0.45) ALDH1A1LMNATSHRTP53MAPK1
SCHEMBL14967318 0.85 PPARG (0.50) ALDH1A1PPARGLMNATSHRTP53
SCHEMBL14967092 0.85 MIF (0.41) MIFALDH1A1PPARGLMNANPFFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed