SCHEMBL14968175

SCHEMBL14968175

CCCCCCOC(=O)C1OC1(CC)c1ccc(OC)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.39
MIF P14174 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.37
STS P08842 4/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967743 0.99 MIF (0.39) PPARGMIFALDH1A1TSHRLMNA
SCHEMBL14967638 0.96 MIF (0.41) MIFALDH1A1TSHRLMNA
SCHEMBL14967899 0.90 CHRM2 (0.37) MIFALDH1A1TSHRLMNA
SCHEMBL16109766 0.88 PPARG (0.41) PPARGALDH1A1TSHRLMNATP53
SCHEMBL14967318 0.86 PPARG (0.50) PPARGALDH1A1TSHRLMNATP53
SCHEMBL16109650 0.86 PPARG (0.39) PPARGALDH1A1TSHRLMNATP53
SCHEMBL14968209 0.85 PPARG (0.41) PPARGMIFALDH1A1TSHRLMNA
SCHEMBL14967067 0.85 PPARG (0.48) PPARGALDH1A1TSHRLMNATP53
SCHEMBL16108654 0.85 TSHR (0.37) PPARGALDH1A1TSHRLMNA
SCHEMBL14967027 0.85 ALDH1A1 (0.45) ALDH1A1TSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed