SCHEMBL14967771

SCHEMBL14967771

CCCCCOC(=O)C1(c2ccccc2)OC12CCCCC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
PRCP P42785 3/20 0.44
SIGMAR1 Q99720 3/20 0.44
GAA P10253 2/20 0.44
POLB P06746 1/20 0.44
APOBEC3A P31941 3/20 0.43
APOBEC3G Q9HC16 3/20 0.43
CHRM2 P08172 2/20 0.43
CHRM1 P11229 2/20 0.43
HTT P42858 2/20 0.43
TSHR P16473 3/20 0.43
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
TMEM97 Q5BJF2 2/20 0.41
KDM4E B2RXH2 1/20 0.41
SLC22A1 O15245 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966845 0.99 ALDH1A1 (0.47) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14967728 0.99 ALDH1A1 (0.49) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14966695 0.98 ALDH1A1 (0.48) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14968095 0.96 ALDH1A1 (0.49) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14967995 0.96 ALDH1A1 (0.46) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14968203 0.95 ALDH1A1 (0.46) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14967839 0.95 ALDH1A1 (0.50) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14967157 0.93 ALDH1A1 (0.47) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14967001 0.91 PRCP (0.47) ALDH1A1PRCPSIGMAR1GAAPOLB
SCHEMBL14968336 0.90 PRCP (0.48) ALDH1A1PRCPSIGMAR1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed