SCHEMBL14967995

SCHEMBL14967995

CCCCCOC(=O)C1(c2ccccc2)OC12CCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 3/20 0.43
CYP3A4 P08684 3/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 3/20 0.43
PRCP P42785 2/20 0.43
SIGMAR1 Q99720 2/20 0.43
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
APOBEC3A P31941 2/20 0.42
APOBEC3G Q9HC16 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
HTT P42858 2/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968203 0.99 ALDH1A1 (0.46) ALDH1A1TSHRCYP3A4TP53MAPK1
SCHEMBL14967728 0.97 ALDH1A1 (0.49) ALDH1A1TSHRCYP3A4TP53MAPK1
SCHEMBL14966695 0.96 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4TP53MAPK1
SCHEMBL14967771 0.96 ALDH1A1 (0.48) ALDH1A1TSHRCYP3A4TP53MAPK1
SCHEMBL14967157 0.96 ALDH1A1 (0.47) ALDH1A1TSHRCYP3A4LMNAPRCP
SCHEMBL14966845 0.95 ALDH1A1 (0.47) ALDH1A1TSHRCYP3A4TP53MAPK1
SCHEMBL14967839 0.94 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4LMNAPRCP
SCHEMBL14968095 0.93 ALDH1A1 (0.49) ALDH1A1TSHRCYP3A4MAPK1LMNA
SCHEMBL14967533 0.91 PRCP (0.45) ALDH1A1TSHRCYP3A4LMNAPRCP
SCHEMBL14967346 0.89 OPRM1 (0.38) ALDH1A1TSHRCYP3A4TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed