SCHEMBL14967911

SCHEMBL14967911

CC1(C(=O)OC2CCCCC2)OC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.47
FABP5 Q01469 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
CHRM3 P20309 3/20 0.42
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
CHRM5 P08912 2/20 0.41
CHRM1 P11229 2/20 0.41
ALDH1A1 P00352 2/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RAB9A P51151 2/20 0.39
LMNA P02545 1/20 0.39
FAAH O00519 1/20 0.39
MGLL Q99685 1/20 0.39
TP53 P04637 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968109 0.99 FABP7 (0.45) FABP7FABP5TDP1CHRM3CHRM2
SCHEMBL14967905 0.96 FABP7 (0.42) FABP7FABP5TDP1CHRM3CHRM2
SCHEMBL14967810 0.93 CHRM3 (0.39) FABP7FABP5TDP1CHRM3CHRM2
SCHEMBL16110307 0.88 TP53 (0.40) FABP7FABP5TDP1ALDH1A1ALOX15
SCHEMBL16109509 0.86 TP53 (0.39) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16109080 0.85 TP53 (0.41) ALDH1A1RAB9ATP53SMN1; SMN2MEN1
SCHEMBL14968168 0.84 ALDH1A1 (0.41) ALDH1A1MAPK1HSD17B10RAB9ATP53
SCHEMBL16109495 0.83 CHRNA1 (0.41) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14968131 0.83 FABP7 (0.44) FABP7FABP5TDP1CHRM3CHRM2
SCHEMBL14968085 0.81 CHRM3 (0.42) FABP7FABP5TDP1CHRM3CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed