SCHEMBL16110307

SCHEMBL16110307

Cc1ccc(C2OC2(C)C(=O)OC2CCCCC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.40
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 2/20 0.39
MAPK1 P28482 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK10 P53779 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
ITGA5 P08648 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
SLC6A2 P23975 1/20 0.38
CHRNB4 P30926 1/20 0.38
SLC6A4 P31645 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CHRND Q07001 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109509 0.99 TP53 (0.39) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16109495 0.96 CHRNA1 (0.41) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16108686 0.93 SCN1A (0.38) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967911 0.88 FABP7 (0.47) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16109080 0.87 TP53 (0.41) TP53ALDH1A1SLC6A4SLC6A3MEN1
SCHEMBL14968109 0.86 FABP7 (0.45) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14968168 0.85 ALDH1A1 (0.41) TP53ALDH1A1MAPK1HSD17B10SLC6A2
SCHEMBL14967905 0.83 FABP7 (0.42) ALDH1A1ALOX15MAPK1HSD17B10TDP1
SCHEMBL14967997 0.83 TP53 (0.38) TP53ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16109534 0.83 SLC6A4 (0.42) TP53ALDH1A1HSD17B10SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed