SCHEMBL14968015

SCHEMBL14968015

CCCCCOC(=O)C1OC1C

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
EPHX1 P07099 1/20 0.44
TSHR P16473 3/20 0.43
ALDH1A1 P00352 1/20 0.42
HCAR2 Q8TDS4 2/20 0.42
PPARG P37231 3/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967824 0.98 NAAA (0.50) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL9566682 0.94 ALDH1A1 (0.48) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL9566680 0.94 ALDH1A1 (0.48) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL9566677 0.94 ALDH1A1 (0.48) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL11187086 0.88 NAAA (0.50) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967926 0.86 PPM1B (0.47) TSHRALDH1A1HCAR2
SCHEMBL2175986 0.83 TSHR (0.36) TSHRALDH1A1
SCHEMBL14967694 0.81 NAAA (0.44) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967866 0.80 NAAA (0.47) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL11396662 0.79 NAAA (0.46) NAAAEPHX1TSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed