⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21961609 | 0.78 | SHBG (0.30) | — | |
| SCHEMBL7934764 | 0.78 | SHBG (0.30) | — | |
| SCHEMBL483052 | 0.73 | — | — | |
| SCHEMBL8352577 | 0.71 | — | — | |
| SCHEMBL18792907 | 0.71 | — | — | |
| SCHEMBL25184830 | 0.71 | MGAM (0.31) | — | |
| SCHEMBL43059 | 0.71 | SHBG (0.37) | — | |
| SCHEMBL14450210 | 0.70 | CYP1A2 (0.34) | — | |
| SCHEMBL28050301 | 0.69 | GAA (0.42) | — | |
| SCHEMBL11877444 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303599-A1 | PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2023-09-28 | — | — | US | disclosed |
| EP-4192474-A1 | PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-116194144-A | Prodrugs of phosphoramide nucleotide analogs and pharmaceutical uses thereof | 吉利德科学公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |