SCHEMBL14968129

SCHEMBL14968129

Cc1ccc(C2(C(=O)OC3CCCC3)OC23CCCC3)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.38
ADORA2B P29275 6/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 2/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK10 P53779 1/20 0.36
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967434 0.99 CHRM3 (0.40) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14967591 0.99 CHRM3 (0.40) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14968179 0.99 CHRM3 (0.40) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14967377 0.97 CHRM3 (0.38) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14967791 0.97 ADORA2B (0.37) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL16109791 0.96 CHRM3 (0.40) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14968162 0.96 TDP1 (0.39) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14967465 0.96 CHRM3 (0.39) CHRM3ADORA2BTDP1ALDH1A1MAPT
SCHEMBL14967388 0.95 ADORA2B (0.37) CHRM3ADORA2BTDP1ALDH1A1ALOX15
SCHEMBL14967022 0.95 CHRM3 (0.41) CHRM3ADORA2BTDP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed