SCHEMBL14968162

SCHEMBL14968162

Cc1ccc(C2(C(=O)OC3CCCCC3)OC23CCC3)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPK10 P53779 1/20 0.38
CHRM3 P20309 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADORA2B P29275 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
EPHX1 P07099 1/20 0.35
METAP2 P50579 1/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967791 0.99 ADORA2B (0.37) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967434 0.97 CHRM3 (0.40) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14968179 0.97 CHRM3 (0.40) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967591 0.97 CHRM3 (0.40) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967388 0.96 ADORA2B (0.37) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14968129 0.96 CHRM3 (0.38) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL16109791 0.95 CHRM3 (0.40) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967239 0.95 CHRM3 (0.36) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967377 0.94 CHRM3 (0.38) TDP1ALDH1A1ALOX15MAPK1HSD17B10
SCHEMBL14967022 0.94 CHRM3 (0.41) TDP1ALDH1A1ALOX15MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed